How different are AMELX & AMELY and what specifically are they testing for? Is it possible a species mutation in the Y variant made it look more like the X variant in the tests? Can they do whole protein mass spec to verify the protein identity?
Okay, I found the paper, they did test by mass spec though it’s complicated by degradation. Still, they say there are 23 diagnostic amino acid substitutions, and of the 18 residue polymorphisms the species only has two, so probably not a back mutation misinterpretation. I agree with their analysis.
Yeah, I don’t know. That’s the extent of my expertise. If the archaeology people say it’s the woman-cave, they probably know best.
How different are AMELX & AMELY and what specifically are they testing for? Is it possible a species mutation in the Y variant made it look more like the X variant in the tests? Can they do whole protein mass spec to verify the protein identity?
Okay, I found the paper, they did test by mass spec though it’s complicated by degradation. Still, they say there are 23 diagnostic amino acid substitutions, and of the 18 residue polymorphisms the species only has two, so probably not a back mutation misinterpretation. I agree with their analysis.
Yeah, I don’t know. That’s the extent of my expertise. If the archaeology people say it’s the woman-cave, they probably know best.