The World Health Organisation reports that globally, about 10% of pregnant women and 13% of women who have just given birth experience a mental disorder, primarily depression. In developing countries, this rate is even higher.

Yet there are few treatments that target the biological changes driving these disorders.

Our research aims to understand how the brain adapts during pregnancy and early motherhood to support healthy mood, with the goal of developing better ways to prevent and treat poor peripartum mental health.

We also hope this work will help reduce the stigma faced by parents who struggle to bond with their baby. Rather than personal failing, difficulties with bonding may reflect brain pathways that have not adapted as expected.

Given the profound changes the brain undergoes during pregnancy, it is perhaps unsurprising that this process does not always unfold smoothly. Parents and families deserve better understanding, support and treatment during this critical period.

There aren’t treatments yet it seems but it’s worth knowing what’s happening.