Is it safe?

I know estradiol pills fuck liver so I can fix this problem by switching to injections but I wonder if this is the case with progesterone?

I can’t do the buffing stuff every night, sorry lol.

  • Hildegarde@lemmy.blahaj.zone
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    3 days ago

    Estradiol pills are processed in the liver. If you take them sublingually they’re mostly not. You absorb more and it has a shorter half life, so may need to be dosed differently. Injections avoid the liver too.

    The main concern I have heard about oral progesterone is that its much less effective that way. I don’t think liver health is a major concern for oral progesterone. I’m getting HRT through my doctor, and I picked them very carefully to make sure I had one who was knowledgeable, and they’ve prescribed me oral progesterone. So it’s probably fine.

    If there are liver concerns I would like to know about it too!

    • Sidal Solgun ♀️@lemmy.caOP
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      3 days ago

      My test results post orchi:

      8mg e2 oral 200mg prometrium oral

      Estradiol: 503 pmol/L

      Progesterone: 6.8 nmol/L

      Testosterone: 0.90 nmol/L

      Good?

      • Hildegarde@lemmy.blahaj.zone
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        3 days ago

        I am not an expert, I do not feel comfortable giving feedback on your levels. There are others here who are more knolasgable, and I’m sure they’ll be here in time.